Physical Design Approaches to Polyplex Libraries by Integrating Particle Engineering with Polymer Chemistry


Ramya is deeply interested in investigating physical pathways for polyelectrolyte complexation (or polyplex formation) by integrating particle engineering, polymer chemistry, and process intensification. This modular approach will create multidimensional libraries of nanoparticles wherein particle morphology and size distribution will be decoupled from the surface composition.

By extending the polyplex design space from chemical to physical dimensions, she wishes to examine the impact of overlooked physical variables and provide biologically validated design guidance for engineering polyplexes with greatly enhanced complexity and functionality.